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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of age-related macular degeneration (AMD)
ncRNA name VEGF shRNA
ncRNA Category shRNA
Disease name age-related macular degeneration (AMD)
Species Mus musculus
Tissues/Cell_line retinas
Methods shRNA knockdown, RT‐PCR, immunohistochemistry, fluorescein angiography
Expression pattern associated
Functional description Subretinal administration of self-complementary (sc)-AAV2/8 encoding anti-VEGF shRNAs can impair vessel formation.
PubMed ID 24953666
Year 2014
Title Development of gene therapy for treatment of age-related macular degeneration.
Drug-related ncRNA NA

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